:root {
  color-scheme: light;
  --bg: #f6f7f4;
  --surface: #ffffff;
  --ink: #1e2723;
  --muted: #647067;
  --line: #d9dfd8;
  --accent: #1d6f58;
  --accent-2: #b45f3a;
  --warn: #8a451f;
  --shadow: 0 14px 38px rgba(25, 45, 36, 0.1);
}

* {
  box-sizing: border-box;
}

body {
  margin: 0;
  min-height: 100vh;
  font-family:
    "Yu Gothic UI",
    "Meiryo",
    system-ui,
    sans-serif;
  background: var(--bg);
  color: var(--ink);
}

.app {
  width: min(1180px, calc(100% - 32px));
  margin: 0 auto;
  padding: 28px 0 40px;
}

.toolbar {
  display: grid;
  grid-template-columns: minmax(240px, 0.9fr) minmax(320px, 1.4fr);
  gap: 20px;
  align-items: end;
  padding: 24px;
  background: var(--surface);
  border: 1px solid var(--line);
  border-radius: 8px;
  box-shadow: var(--shadow);
}

.eyebrow {
  margin: 0 0 6px;
  color: var(--accent);
  font-size: 0.78rem;
  font-weight: 700;
  text-transform: uppercase;
}

h1,
h2,
p {
  margin: 0;
}

h1 {
  font-size: clamp(1.75rem, 2.4rem, 2.4rem);
  font-weight: 800;
}

.controls {
  display: grid;
  grid-template-columns: 1.2fr 140px 110px;
  gap: 12px;
}

label {
  display: grid;
  gap: 6px;
  color: var(--muted);
  font-size: 0.82rem;
  font-weight: 700;
}

input,
select {
  min-height: 42px;
  width: 100%;
  border: 1px solid var(--line);
  border-radius: 6px;
  padding: 0 12px;
  color: var(--ink);
  background: #fbfcfa;
  font: inherit;
}

input:focus,
select:focus {
  outline: 3px solid rgba(29, 111, 88, 0.16);
  border-color: var(--accent);
}

.summary {
  display: flex;
  align-items: center;
  gap: 14px;
  margin: 18px 0;
  color: var(--muted);
}

.summary div {
  display: inline-flex;
  align-items: baseline;
  gap: 4px;
  min-width: 64px;
  color: var(--accent);
  font-weight: 800;
}

#resultCount {
  font-size: 2rem;
}

.drug-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 16px;
}

.drug-card {
  min-height: 330px;
  display: flex;
  flex-direction: column;
  gap: 16px;
  padding: 20px;
  background: var(--surface);
  border: 1px solid var(--line);
  border-radius: 8px;
}

.drug-card header {
  display: flex;
  justify-content: space-between;
  gap: 12px;
  align-items: start;
}

.generic {
  margin-bottom: 4px;
  color: var(--muted);
  font-size: 0.85rem;
  font-weight: 700;
}

h2 {
  font-size: 1.25rem;
  line-height: 1.35;
}

.species {
  flex: 0 0 auto;
  border: 1px solid rgba(29, 111, 88, 0.28);
  border-radius: 999px;
  padding: 5px 10px;
  color: var(--accent);
  background: rgba(29, 111, 88, 0.08);
  font-size: 0.78rem;
  font-weight: 800;
}

dl {
  display: grid;
  gap: 10px;
  margin: 0;
}

dl div {
  display: grid;
  grid-template-columns: 74px 1fr;
  gap: 12px;
}

dt {
  color: var(--muted);
  font-size: 0.78rem;
  font-weight: 800;
}

dd {
  margin: 0;
  line-height: 1.55;
}

.calculated-dose {
  color: var(--accent-2);
  font-weight: 800;
}

.notes {
  margin-top: auto;
  padding: 12px;
  border-left: 4px solid var(--warn);
  background: #fff7ef;
  color: #59331e;
  line-height: 1.55;
  font-size: 0.92rem;
}

.empty {
  grid-column: 1 / -1;
  padding: 28px;
  background: var(--surface);
  border: 1px dashed var(--line);
  border-radius: 8px;
  color: var(--muted);
  text-align: center;
}

@media (max-width: 820px) {
  .toolbar,
  .controls,
  .drug-grid {
    grid-template-columns: 1fr;
  }

  .toolbar {
    padding: 18px;
  }

  .summary {
    align-items: flex-start;
  }
}

@media (max-width: 520px) {
  .app {
    width: min(100% - 20px, 1180px);
    padding-top: 12px;
  }

  dl div {
    grid-template-columns: 1fr;
    gap: 4px;
  }
}